Gavin C K W Koh Selected Research

Cytochrome P-450 CYP2D6 (CYP2D6)

2/2016

Tafenoquine treatment of Plasmodium vivax malaria: suggestive evidence that CYP2D6 reduced metabolism is not associated with relapse in the Phase 2b DETECTIVE trial.

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Gavin C K W Koh Research Topics

Disease

10	Vivax Malaria 02/2024 - 02/2016
10	Melioidosis 09/2020 - 10/2010
6	Infections 01/2023 - 03/2011
4	COVID-19 09/2023 - 01/2022
3	Tuberculosis (Tuberculoses) 02/2024 - 01/2013
3	Sepsis (Septicemia) 01/2013 - 12/2011
2	Thrombocytopenia (Thrombopenia) 09/2020 - 01/2017
2	Typhoid Fever (Typhoid) 04/2015 - 08/2014
2	Diabetes Mellitus 06/2012 - 03/2011
1	Pulmonary Tuberculosis 02/2024
1	Disease Progression 10/2022
1	Parasitemia 01/2019
1	Glucosephosphate Dehydrogenase Deficiency 12/2016
1	Body Weight (Weight, Body) 12/2016
1	Shock 04/2015
1	Colitis 08/2014
1	Inflammation (Inflammations) 08/2014
1	Vitamin D Deficiency 01/2013
1	Chronic Disease (Chronic Diseases) 01/2013
1	Critical Illness (Critically Ill) 06/2012
1	Acute Lung Injury 06/2012
1	Latent Infection 01/2012
1	Candidemia 12/2010

Drug/Important Bio-Agent (IBA)

10	tafenoquineIBA 02/2024 - 02/2016
4	cilgavimabIBA 09/2023 - 01/2022
4	tixagevimabIBA 09/2023 - 01/2022
3	cilgavimab and tixagevimab drug combinationIBA 09/2023 - 01/2022
3	Primaquine FDA Link 01/2019 - 02/2016
2	AntigensIBA 10/2022 - 01/2017
2	von Willebrand FactorIBA 09/2020 - 01/2017
2	EndotoxinsIBA 01/2017 - 04/2015
2	Thrombin FDA Link 01/2017 - 12/2011
2	CytokinesIBA 01/2017 - 08/2014
2	Glyburide (Glibenclamide)FDA LinkGeneric 01/2013 - 03/2011
1	Amino Acyl-tRNA Synthetases (Aminoacyl-tRNA Synthetase)IBA 02/2024
1	Rifampin (Rifampicin)FDA LinkGeneric 02/2024
1	Antimalarials (Antimalarial Agents)IBA 12/2022
1	Monoclonal AntibodiesIBA 10/2022
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 01/2022
1	LigandsIBA 01/2019
1	Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA 01/2019
1	Toll-Like Receptor 5IBA 01/2019
1	FlagellinIBA 01/2019
1	8-aminoquinolineIBA 01/2018
1	Lumefantrine Drug Combination Artemether (Coartem)FDA Link 12/2016
1	artenimol (dihydroartemisinin)IBA 12/2016
1	piperaquineIBA 12/2016
1	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 02/2016
1	Leukocyte L1 Antigen Complex (Calgranulin)IBA 04/2015
1	Toll-Like Receptor 4IBA 04/2015
1	Proteins (Proteins, Gene)FDA Link 04/2015
1	Interleukin-18 (Interleukin 18)IBA 08/2014
1	3,5-diisopropylsalicylic acid (DIPS)IBA 01/2013
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 01/2013
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2013
1	InterferonsIBA 01/2013
1	Vitamin D FDA LinkGeneric 01/2013
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 06/2012
1	VaccinesIBA 01/2012
1	Attenuated VaccinesIBA 01/2012
1	Protein CIBA 12/2011
1	Prothrombin (Factor II)IBA 12/2011
1	Fibrinogen (Factor I)FDA Link 12/2011
1	Fibrinolysin FDA Link 12/2011
1	AnticoagulantsIBA 12/2011
1	Antifibrinolytic Agents (Antifibrinolytics)IBA 12/2011
1	fibrin fragment D (D-dimer)IBA 12/2011
1	AntithrombinsIBA 12/2011
1	Protein SIBA 12/2011
1	Ceftazidime (Fortum)FDA LinkGeneric 11/2011
1	Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav)FDA Link 11/2011
1	InflammasomesIBA 03/2011
1	Hypoglycemic Agents (Hypoglycemics)IBA 03/2011
1	Adenosine Triphosphate (ATP)IBA 03/2011
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 03/2011
1	Interferon-gamma (Interferon, gamma)IBA 10/2010

Therapy/Procedure

3	Therapeutics 01/2019 - 06/2012
2	Secondary Prevention 01/2019 - 12/2016
2	Drug Therapy (Chemotherapy) 01/2013 - 01/2013
1	Duration of Therapy 02/2024
1	Intramuscular Injections 01/2023
1	Central Venous Catheters 12/2010